METAL CHELATES OF SULFAFURAZOLE AZO DYE DERIVATIVE: SYNTHESIS, STRUCTURE AFFIRMATION, ANTIMICROBIAL, ANTITUMOR, DNA BINDING, AND MOLECULAR DOCKING SIMULATION

Metal Chelates of Sulfafurazole Azo Dye Derivative: Synthesis, Structure Affirmation, Antimicrobial, Antitumor, DNA Binding, and Molecular Docking Simulation

A series of divalent and one trivalent metal chelates of the azo ligand resulting from coupling of sulfafurazole diazonium chloride with resorcinol have been designed and synthesized.Structure investigation of the isolated chelates have been achieved by applying spectroscopic and analytical tools which collaborated to assure the formation of the me

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Calculating and comparing codon usage values in rare disease genes highlights codon clustering with disease-and tissue- specific hierarchy.

We designed a novel strategy to define codon usage bias (CUB) in 6 specific small cohorts of human genes.We calculated codon usage (CU) values in 29 non-disease-causing (NDC) and 31 disease-causing (DC) human genes which are highly expressed in 3 distinct tissues, kidney, muscle, and skin.We applied our strategy to the same selected genes annotated

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A new approach for dry metal forming: CO2 as volatile lubrication in combination with hard and low friction coatings

Nowadays, it is more important than ever to meet the increasing technical and statutory requirements and to develop new process strategies.In sheet metal forming the low consumption of oil lubrication gets an increasingly important role.The aim in sheet metal forming is to reduce the amounts of lubricants.In the long term, the future sheet metal pr

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Outcomes of different steroid dosing regimens in critical Covid-19 pneumonia at a Kenyan hospital: A retrospective cohort study.

BackgroundAmong therapeutic options for severe and critical COVID- 19 infection, dexamethasone six milligrams once daily for ten days has demonstrated mortality benefit and is guideline recommended at this dose.In practice, variable doses of steroids have been used, especially in critical care settings.Our study aimed to determine the pattern of st

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